In detail

Causes of miscarriage

Causes of miscarriage

Spontaneous abortion represents a loss of pregnancy due to natural causes. His appearance in the first trimester of pregnancy is often a mystery to doctors. They do not always succeed in providing a logical explanation for the event. Although many causes are still unknown, specialists have identified a few factors that favor spontaneous abortion.

In some cases, spontaneous abortion occurs even after taking all precautionary measures known in this regard. Although a whole series of analyzes are performed with the role of detecting potential conditions that could lead to it, abortion occurs unexpectedly.

It should be known that the analysis of the circumstances, respectively of the causes in which a spontaneous abortion occurs is very rarely undertaken in women who first go through this experience.

It is ordered to proceed to investigations in this regard when there is a cyclicality of the miscarriage in the same woman.

Physiological causes

Chromosomal abnormalities

In the classic definition of miscarriage it should occur within the first three months of pregnancy (up to 12 weeks). When it follows the rule, the cause is a chromosomal one: the embryo is not well formed, and the concept stops evolving.

There are situations where a pregnancy occurs by developing an embryo that seems to be normal. If at the time of its formation there were certain chromosomal abnormalities, it will be affected and it will stop from evolution, thus spontaneous abortion will occur.

Malformations of the uterus

The most common cause of miscarriage is considered:

  • septate uterus, unicorn, bicorn etc;

  • uterine fibroids;

  • uterine synechia.

Endocrine disorders or disorders

  • luteal insufficiency;

  • polycystic ovary syndrome;

  • hypersecretion of luteinized hormone;

  • thyroid dysfunction;

  • insufficient progesterone and estrogen;

  • Cushing's syndrome, etc.


  • virotic infections;

  • chronic infections (syphilis, tuberculosis);

  • acute infections (pneumonia, whooping cough, rubella, listeriasis, toxoplasmosis, influenza);

  • intestinal infections (dysentery, food poisoning).

Chronic diseases

  • diabetes;

  • kidney disease;

  • hypertension;

  • anemia;

  • constipation;

  • cardiovascular diseases;

  • lung disease.

Autoimmune diseases

  • systemic lupus erythematosus;

  • psoriasis;

  • autoimmune thyroiditis Hashimoto;

  • rheumatoid arthritis;

  • Crohn's disease etc.

Risk factors

Another cause of miscarriage comes from the genetic inheritance of the woman and her lifestyle. These are rather risk factors, as there is no reliable and scientifically proven certainty of their validity in the production of spontaneous abortion. However, the statistics and investigations carried out around them have revealed a close causal link between them and the abortion in question:

  • age - the longer a woman becomes pregnant (over 35 years), the risk of spontaneous abortion increases (25%);

  • alcohol consumption during pregnancy;

  • smoking;

  • excessive caffeine intake during pregnancy;

  • drug use;

  • history of miscarriages;

  • improper administration of certain drugs during pregnancy (eg antibiotics);

  • physical overload (prolonged physical exertion) - labor intensive, carat weight, excessive sport - all represent potential causes of spontaneous abortion;

  • exposure to various pesticides and toxic chemicals;

  • malnutrition.

Tags Causes of miscarriage Risk of miscarriage